Nailfold capillaroscopy and microvascular involvement in Diabetes Mellitus

Objective: to study the relationship between microvascular lesions of Diabetes Mellitus and alterations in nailfold capillaroscopy. Subjects Methods: cross-sectional including 140 individuals (70 with 70 controls). Epidemiological clinical variables were collected from patient’s charts. Fundus ophthalmoscopy, capillaroscopy, analysis microalbuminuria renal clearance as well fasting glycaemia HbA1c values studied simultaneously.Results: capillary density was reduced, vascular dilatation increased patients when compared controls (both p<0.0001). In diabetic number dermal papillary capillaries/mm3 correlated negatively (p=0.02), age (p=0.03), (p=0.03). Patients retinopathy using antiplatelet agents had lower (p<0.0001 0.04 respectively). Capillary associated disease duration (p=0.04).Conclusion: is reflected Decreased density, ectasias presence avascular areas observed diabetes controls. present study, correlated/ associate age, retinopathy, use medication, HbA1c, duration. Ectasias or dilatations related glomerular filtration rate longer